Brain  Tumors  and
Other Diseases of the Central Nervous System
Cases  Correlating  Neuroimaging and  Neuropathology
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Updated 5/1/2020 e-mails : [email protected]___[email protected] 
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Additions  2003 - 2006
2007 - 2010
2011 - 2014 2015 -  2018 2019 to present
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General and Special Pathology  Neuropathology and Neuroimaging Neuroimaging Basics Neuroimaging - Cases
Alphabetical index (Pathology) Alphabetical index (Neuro) Neuro Image Bank Neuropathology - Cases
English Homepage This page in Portuguese Histological techniques New additions
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Cases  posted  in  2015 to 2018
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22/11/18
M. 5 yr 5 m.   Desmoplastic medulloblastoma  with rhabdomyoblastic differentiation (medullomyoblastoma) M. 8 yr 10 m Pleomorphic xanthoastrocytoma
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M. 3 yr 9 m.  Clear cell meningioma of cauda equina F. 3 yr. Tuberculoma of thalamus
M. 5 yr 5 m  Mature teratoma of pineal F. 44 yr.   Cerebral neuroenteric cyst
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9/9/18
M. 5 yr 2 m.   Melanotic medulloblastoma of cerebellar vermis F.  7 m.  Atypical teratoid/rhabdoid tumor of cerebellar vermis
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F. 7 yr  6 m.   Temporo-occipital dysembryoplastic neuroepithelial tumor (DNT) M. 17 yr 2 m.  Recurrent cerebral metastases of yolk sac tumor of testis.  Third lesion at same site within one year
F. 3 yr 4 m.  Malignant rhabdoid tumor of kidney F. 4 yr 3 m. Same case - cerebral metastasis one year after complete clearing of systemic  lesions by chemotherapy
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7/7/18
F. 8 yr 5 m.   Rosai-Dorfman disease of brain (non-Langerhans histiocytosis)  F. 4 yr 1 m. 
Anaplastic ganglioglioma of thalamus (grade III) evolving to grade I after radio- and chemotherapy
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F. 11 yr 1 m. Ganglioglioma of deep cerebral white matter M. 6 yr 3 m. Ganglioglioma of cervicothoracic spinal cord
M. 3 yr 1 m. Choroid plexus carcinoma of right lateral ventricle F. 3 yr.  Choroid plexus carcinoma of right lateral ventricle  before and after chemotherapy
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14/05/18
M. 7 m. 28 d. Desmoplastic infantile  ganglioglioma (DIG) F. 6 yr. 8 m.  Classical medulloblastoma in fourth ventricle;  retrograde seeding of third ventricle mimicking germinoma
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M. 16 yr.  Yolk sac tumor of testis with two brain metastases at different times M. 19 yr. Embryonal carcinoma originating in immature teratoma of testis.  Two brain metastases at different times
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20/03/18
M. 9 yr 6 m.  Classical medulloblastoma in cerebellar vermis, rich in nuclear palisading and Homer Wright pseudorosettes. Temporal lobe metastasis after 8 years, faithfully recapitulating the original tumor,  with no recurrence at the primary site F. 5 yr. Classical medulloblastoma in cerebellar vermis. Recurrence at primary site after 9 years, progression via III ventricle and foramina of Monro to  large  frontal lobe metastasis 
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M. 5 yr 3 m. Primitive neuroectodermal tumor (PNET) of temporal lobe  M. 15 yr.  Germinal cell tumor of III ventricle (germinoma in a small biopsy)
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15/1/18
M. 2 m 12 d Medulloblastoma with extensive nodularity M. 10 yr 2 m.  Ectopic subcutaneous myxopapillary ependymoma of sacral region
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M. 1 yr 3 m.  Diffuse multicystic ganglioglioma in cerebellum  F. 10 yr 4 m.  Cerebellar ganglioglioma with pilocytic glial component  +  NF1
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F. 1 yr 1 m  Sacrococcygeal teratoma with yolk sac tumor (or endodermal sinus tumor) component M. 12 yr.  Giant cell reparative granuloma of mastoid
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30/09/17
F. 1yr 1m. Anaplastic ganglioglioma  in III ventricle. Original biopsy and after 6 months of chemotherapy F. 1yr 3m. Extensive thoracic myxopapillary ependymoma 
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M. 19 yr. Diffuse low grade astrocytoma of thoracic spinal cord.  Spread to cauda equina and frontal metastasis F. 14 yr.  Colloid cyst of III ventricle
F. 22 yr.  Colloid cyst of III ventricle M. 55 yr.  Colloid cyst of III ventricle
M. 6 yr.  Langerhans cell histiocytosis (histiocytosis X or eosinophil granuloma) of skull (occipital bone) F. 2yr 9m. Langerhans cell histiocytosis  in vertebral body of C7
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13/06/17
M. 7 yr. 8 m. Cerebral meningioangiomatosis M. 10 m. Choroid plexus papilloma of lateral ventricle 
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F. 3 m. 15 d.  to  3 yr. 4 m. 
Anaplastic congenital glioma with spontaneous maturation and regression.  3-year follow-up
F. 2 yr 9 m.  Embryonal tumor with abundant neuropil and multilayered rosettes.  Recurrence after 6 months. 
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20/1/17
F. 79 yr. Gangliocytoma of pituitary.  M. 2 yr. 4 m.  Anaplastic ganglioglioma of brain stem. 
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M. 46 yr. Eosinophil pituitary adenoma causing acromegaly.  Negative IH for HGH in spite of increased serum levels.  F. 46 yr.  Progressive multifocal leukoencephalopathy (PML). 
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M. 18 yr.  Dermoid cyst of posterior fossa insinuating into foramen magnum and compressing medulla.  F. 47 yr.  Cysticercus racemosus of brain.
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30/11/16
M. 1 yr. 1 m. Atypical teratoid/rhabdoid tumor Pictured - INI1 negativity  in neoplastic cells, positive control in endothelium M. 18 yr. Dysembryoplastic neuroepithelial tumor.  Pictured - floating neuron
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M. 20 yr.  Brain and lung metastases of testicular choriocarcinoma. M. 7 yr. 2 m. Glioblastoma multiforme of thalamus. 
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31/8/16
F. 2 yr.  2 m. Embryonal tumor with abundant neuropil and multilayered rosettes F. 72 yr. Cerebral amyloid angiopathy, parenchymatous and ventricular hemorrhage
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F. 8 yr.  Ganglioglioma with pilocytic astrocytoma component in spinal cord M. 23 yr. Cystic ganglioglioma with minute solid component of pilocytic astrocytoma in cingulate gyrus
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F. 4 yr.  Diffuse anaplastic astrocytoma of pons  M. 11 yr.  Glioblastoma multiforme of pons
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20/7/16
F. 1 yr. 5 m.   Hemimegalencephaly, agyria, pachygyria. M. 20 yr. Ganglioglioma of head of caudate nucleus 
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M. 15 yr.  Atypical central neurocytoma of third ventricle F. 24 yr.  Desmoplastic medulloblastoma
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5/5/16
M. 1 yr. 9 m. Tuberous sclerosis. Giant partly calcified fronto-parietal tuber M. 4 yr. 4 m.  Subependymal giant cell astrocytoma in tuberous sclerosis
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M. 23 yr. Frontal giant cell glioblastoma  M. 25 yr.   Neurofibromatosis type 2. Ependymomas in medulla and lumbar spinal cord; bilateral vestibular and right oculomotor schwannomas; meningioma of optic nerve sheath, others
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F. 55 yr. Fibroblastic S-100 positive meningiomas of posterior fossa raising schwannoma as differential diagnosis  M. 74 yr. Fibroblastic S-100 positive meningioma of posterior fossa at internal auditory canal mimicking schwannoma
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20/2/16
M. 32 yr.   Neurotuberculosis in rare presentation with symmetrical necrotizing vasculitis of midline cerebral cortex and corpus callosum M. 63 yr.   Fronto-temporal gliosarcoma 
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M. 51 yr. Pilocytic astrocytoma of cerebellum with unusually luxuriant capillary proliferation (prompting differential diagnosis with hemangioblastoma) F. 67 yr.  Pilocytic astrocytoma of retina
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M. 64 yr. Pseudotumoral paracoccidioidomycosis  of cerebellum F. 21 yr.  Fibrous dysplasia of skull 
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27/12/15
F. 62 yr.   Massive subarachnoid hemorrhage secondary to systemic aspergillosis and leptomeningeal vasculitis F. 67 yr.  Rhino-orbital aspergillosis
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F. 31 yr.  Cysticercosis cellulosae of brain hemispheres and IV ventricle M. 8 mth. Congenital cerebral teratoma
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4/11/15
F. 32 yr.   Dysplastic gangliocytoma of  cerebellum  (Lhermitte-Duclos disease)  M. 22 yr.   Dysplastic gangliocytoma of  cerebellum  (Lhermitte-Duclos disease)
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F. 45 yr.   Dysplastic gangliocytoma of  cerebellum  (Lhermitte-Duclos disease). Two distinct lesions in right cerebellar hemisphere M. 32 yr.   Cerebral  granulomatous cryptococcosis: circumscribed meningeal, cerebral lesions 
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5/10/15
F. 6 yr 7 m.   Angiocentric glioma  in left superior frontal gyrus F. 57 yr.   Primary cerebral vasculitis
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18/5/15
F. 37 yr.   Pituitary carcinoma  with pulmonary metastases. 6-year follow up. F. 70 yr. Rathke's cleft cyst. 
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M. 36 yr.   Fronto-parietal mesial pleomorphic xanthoastrocytoma M. 11 yr. Frontal pleomorphic xanthoastrocytoma
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M. 11 yr. 6 m. Intradural cervical and lumbar lipomas. F. 62 yr. Thoracic epidural meningeal cyst 
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20/2/15
F. 20 yr.    Anaplastic and clear cell  meningioma of posterior fossa with supratentorial extension. F. 26 days.  Congenital anaplastic astrocytoma of temporal lobe.
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F. 67 yr.   Invasive pituitary adenoma with extensive skull base infiltration. F. 22 yr.  Cerebral metastases of choriocarcinoma 6 years after molar pregnancy.
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Updated 5/1/2020 e-mails : [email protected]___[email protected] 
...
Additions  2003 - 2006
2007 - 2010
2011 - 2014 2015 -  2018 2019 to present
....
General and Special Pathology  Neuropathology and Neuroimaging Neuroimaging Basics Neuroimaging - Cases
Alphabetical index (Pathology) Alphabetical index (Neuro) Neuro Image Bank Neuropathology - Cases
English Homepage This page in Portuguese Histological techniques New additions
.....